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Home arrow newsitems arrow Virus: Biggest Ever Trial on HCQ+AZ+Zinc Cure (3.700 Patients) Found World-Record Survival: 99,5 % !

Virus: Biggest Ever Trial on HCQ+AZ+Zinc Cure (3.700 Patients) Found World-Record Survival: 99,5 % !

Parašė ACM
lundi, mai 25, 2020

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*Strasbourg/Angelo Marcopolo/- In the Biggest Trial Study of HCQ+AZ+ against the Virus, just Concluded this Month, among about 3.700 Patients (i.e. the Larger Ever in the World in that area, until now), the Mortality Rate was Only ...0,5%, giving a Global Record-Breaking Survival Rate of 99,5%, as Announced Today French Professor Dr. Didier Raoult, an Experienced and Famous Infectiologist/MicroBiologist Expert, CEO of Mediterranean and Infection Hospitalo-Universitarian Institute (IHU) at Marseille City, who had been already EnTrusted by Historic French President Jacques Chirac (a Gaullist) to daft a 1st Report for the Strategy of the Country's Protection from any foreseable Risk of Epidemic, already, as Early as since the Beginning of 2000ies, (just After the SARS-1 Virus of 2003+).

- Moreover, among those circa 3.700 Patients "retrospectively", treated with HCQ+AZ+ Nowadays, "we NEVER Observed Any CARDIAC Death and Toxicity", it was added by the Two main Leaders of that New Trial, (D. Raoult and Matthieu Million), where "7.800 ECG were made" on all those Patients, by measure of Precaution.

+ Already, with  "ZERO (0) Deaths" of People Infected by the COVID-19 Virus "before 70 Years of Age", and just 8 Deaths among Only those Aged "74 to to 95 Years", in a CHQ+ Trial with More than 1.060 Patients, Concluded Previously, at the End of March, and Published at a Scientific Review on May 5, 2020, the Results appeared very Positive, (See Also Infra).

Such Landmark Results also have a Key Importance for Crucial and Topical Issues of International Health Strategy at Global Level, Nowadays :

 - Indeed, the International Health Organisation (WHO), at Nearby Geneva, had Chosen, Among about 50 Various Candidates, ("Based on Evidence from Laboratory, Animal, and [Human] Clinical Studies"), the HCQ+ as 1 Among the 3 Best "Most Promising" Candidate Drugs in the World Deserving to be Tested by its Research Program for Medical Treatment against the CoronoVirus, ("Solidarity"), with 108 Millions $ Funding and about 3.500 Patients from 17 Countries.

Competitors are Only "Remdesivir" (a Failed attempt Initially v. Ebola in Congo, where it did Not work, while Other Drugs did, But Later reportedly used in Animals v. SARS-1, Needing an IntraVenous, and Expensive, Based on Genetic Manipulations expected to Block Virus' Replication, and Backed by "Gilead" Big Pharma Corporation, holding its Patent) ; and "Lopinavir"'s Combinations, (Initialy destinated to "HIV", with "Ambiguous" Results v. SARS-1 or MERS, and "Not Encouraging" First Trials v. COVID-19, it may cause "Significant" Liver Damage, But is now Tested v. MERs in Saudi Arabia).

=> So that HCQ+ appeared, until now, to be, comparatively, the Best Hope for the World Health Organisation. A Succesful Drug already against Malaria and Arthritis, Used withOut Problem Since the 2nd World War, now a "Generic", Cheap and Simple Pill, it Might Protect Cells from Virus' Attacks, Strengthening the Natural Human Immune System, But it must Avoid Side Effects, with right Precautions. About 20 Chinese Studies reportedly were Succesful against this Virus, But a Lack of Full Published "Data" was reported, with the Exception of French Professor Raoult's Tests, that Some considered Initially "InSuficient", until his Recent Work, (which, therefore, has a Crucial Importance Nowadays).

>>> Even More Important, World-wide :  It's a Fact that the WHO has, Until Now, practicaly Excluded Vaccines from its above-mentioned International Research projects, Focused Only on Treatments and Cure, (Comp. Supra), mainly Because of a "Need for Speed", in order to "Reduce the Time" usually taken by Vaccines' testing, (may be 1 or 1,5 Year+), given the Urgency in this Deadly Virus' Crisis. In Consequence, (and given also the Facts cited Supra), at least Until Now, Serious HCQ+ Trials appeared to be, in Practice, probably the Only attainable Hope to Find a way to Urgently Save currently Threatened Human Lives throughout the Planet !

--------------------------------

In this Context, Previously, Trials with HCQ+AZ+ by Prof. Raoult, concluded at the End of March, had Resulted Already High enough, with a 99,1 % Survival rate. But the New Overall Results, which just Concluded on this May, (Including Almost Four Times More Patients : See Infra),  Reached an Even Higher Survival rate : 99,5 % (i.e., by Far, the Best in the World) !

--------------------------------

Professor Raoult's team had Initialy Tested 36 Patients, Afterwards 80, and Later 1.061, whlle Recent Rumours evoked anew a Doubling of the Number of Patients for a New, Bigger Trial,  (i.e. about 2.000). But, Finaly, he Revealed Today that it had just reached, Nowadays, almost a ...Quadripling in Tests, with about 3.700 People Affected by that Deadly Virus !

=> By so doing, obviously, this French Team largely Slamed the Accusations made Recently by a Bogus "Study", led by Dr. Mandeep Mehra, an Indo-Pakistani Cardiologist (sic !) at "Brigham and Women's Hospital" (USA), curiously Published by "LANCET" UK Review, with a Controversial Text, (Only Based on Remote, Automatic retrieval of Registry Data, by Computers' Networks, from 671 Hospitals in 6 Continents of the World, stained by at least 11 Gros Flaws ! See: http://www.eurofora.net/newsflashes/news/bogusmoveagainsthcqdrugvvirus.html), Claiming that the pro-HCQ/AZ Scientists (as Raoult etc) would have been based Only on some ..."Anecdotal Experiences" and "Small Scale Studies" (sic !) for their Theories...

But, Already, Their "6.221" copied Case-Files reportedly Registered as Including HCQ+AZ+ Treatments, in fact, are Not Equivalent to that, but Only in 1/2 or 1/3 of cases, since they doN't concern Only Azythrimycine but Also Any Other among such "    " Category of substances, of which there are 2 or 3, etc... So that, in Fact, Only some 3.110 or even just 2.070, (Perhaps Less) Might concern Professor Raoult's HCQ+AZ Protocol !             

=> I.e., a Smaller amount of strictly "Virtual" Data Remotely and Automatically Retrieved by Computer Networks, than the "More than 3.700 Patients", in Real Physical Cases, Directly Observed and Treated by Prof. Raoult's team Nowadays...                   

--------------------------------

- Indeed, "we made a Very, very Big Study, with More than 3.600 Patients, which Allows us to have a sufficiently Clear View of what is going on", Professor Raoult Announced Today.

- "Most of them were Treated by Associating CHQ + AZ, and, among them, Mortality is O,5%, that is to say, the Lowest in the World !", he stressed.             

=> - "So, ...Here, HCQ+ Saves Many Lives !", he Concluded.

+ Advancing (for the 1st Time), even towards a Control Group approach, he Pointed out that, "By Comparing also with Other Groups" of Patients, "who Came Too Late, Walked Out, or had Counter-Indications, because of their Coditions and Age, etc., so that they were UnAble to receive that HCQ+AZ Treatment, which gives Better Results, but Only got Other, Ordinary Treatments, there was a very Significant Difference"..., and "that's Interesting".

The "HCQ-AZ" Group included more than 3.000 Patients, while more almost 700 were "treated with Other Methods", he added later-on.

=> "Early Diagnosis, ...and Early Treatment, with at least 3 Days of HCQ-AZ, Result in a Significantly Better clinical Outcome", "with a Decreased risk of Transfer to the (Intensive Care) ICU, or  Death , ..., Decreased risk of Hospitalization ≥10 days", ... and Shorter Duration of Viral shedding", (ibid).

++ And, Now, "we Know that some things which (in the Past) had been UnderEstimated, as, f.ex., the ZINC", in fact, "Play a Role in the Severity" of cases, "f.ex. People who have a Severe Pathology, have Lower Zinc Rates than Others, in addition, also, to Other Things, too, which were, meanwhile, registered".

+++ However, "we made also", in Total, "More than 10.000 Electro-Cardio-Grams (ECG), and All were Examined by a Cardiologist", so that there wasN't any Heart Incident here at all, he pointed out. - "By the way", with the due care, "HCQ may affect People Less than... even Dolipran" (a Banal Pain-Killer) "which, in fact, is the 1st Cause in the World for Poisoning !", if taken in an inappropriate way, he extrapolated. - All and all, "we had a Total of 36 Deaths" (throughout All Trials, New and Old), "from which Not even One (1) wasn't Ever related with the Heart".

>>> In General, as a matter of Principle, Prof. Raoult's Team stands for an "Early" and "Carefully Controlled Treatment, with Safe and Well-Tolerated Drugs", "in individuals with Mild Symptoms, Before signs of Severity appear", and "paying Strict Attention ...to Contra-Indications and ...Inter-Actions with concomitant Medication", as he advised, Already in the Conclusions of the Previous Trial (of 1.061 Patients), Published at the Beginning of May, (Comp. Supra).

++++ In Parallel, Additionaly, "we have made about 130.000 Diagnostic Tests by PCR in some 50.000 Patients, including Diagnosis in about 5.000 Cases which were Treated Here", Raoult Noted Today.  

=> - "So that we were among the First to say that", in principle, "Children are Not Infected, are Not Affected" by that Virus, and - "Now, we Know Why !" Something that "we will Reveal Next Week", he promised, by the way.    

  - And "we Know that there are People who are Very Sick, and  have Big Lesions (visible only) at the Scanner, While they are Not Short of Breath", but with "Minimal" "Dyspnoea" (i.e. almost "ASymptomatic", etc).  -

 - So that, "the Evolution of (such) New Diseases canNot always be Foreseen based on that of Older Diseases : Each one may have Its Own Way to Evolve".

 =>  - Thus, "we Accumulated a Considerable Amount of Data, probaly Unique in the World", "from which we Have to Make several Conclusions, Later-on, at the Right Moment - which is Not always Similar to that of the Press-Medias : Everybody lives at his Own Pace"..., he Smiled, giving RDV in a foreseable Future.

 

(../..)

 

("Drafty-News")

 

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They voted to "freeze" UK Government's draft to put People in jail for 42 Days on "anti-terrorist" suspicion without charge, or they abstained. Don't they look suspect ?
-------------------------

CoE's debate on UK controversy stirs PanEuropean check of anti-terror suspects' imprisonment

Former Leftists of the Sixties would boil in hot water if they heard PACE's debate on the controversial 42 days detention without charge, currently drafted by the British Government :

A "Socialist" Government, a Socialist PACE Rapporteur and a Socialist Chair of PACE's Legal Committee, opposed a .. "Conservative" amendment (supported by .. Liberals, Democrats, etc), to freeze the measure, in order to protect Citizens' Freedom, by "waiting" until CoE's Venice Committee checks its conformity with Human Rights' principles.

"Left"'s support to Conservative-Lib.Dem's criticism, wasn't enough to obtain a majority, nor to make things as they were back in the good old days, when "Left" and "Right" had a clear meaning, as "liberty" and "restrictions"...

Conservatives and most Democrats were joined by the Left in voting for the "freeze", as well as Liberal Paul Rowen, while Socialist MEP Ivan Popescu, an experienced MEP from Ukraine (PACE Member since 1996-2008) abstained. But most Socialists, added to a few Liberals and EPP's Right, voted against.

Fortunately, someone inside PACE had the wise idea to shorten the Debate for less than 1 Hour, and put it on the Agenda only at the end of an exceptionally busy day, towards the end of the Evening, when most MEPs had already gone to taste wins and foods at various Receptions all around Strasbourg's "European" area : As a result, not even 42 MEPs weren't present..

Socialist Lord Tomlinson accused the leaders of the PanEuropean Assembly, in its highest body : the "Bureau", to "lack wisdom" by deciding to hold a Debate on an issue that neither the Socialist Chair of the Legal Committee, nor its Socialist "reluctant Rapporteur", did "not want to do", ...

tomllinson

Finally, everybody (critics and supporters alike) was happy to agree, in substance, that the controversial measure "may" gravely violate Human Rights, and therefore, PACE asked Legal Experts of Venice Commission to check UK Government''s plans.

But this might take more than .. 42 Days to do, since PACE's Rapporteur asked the Experts to enlarge their study in a PanEuropean comparison of all that is happening on "anti-terrorism" legislation in 47 CoE Member Countries, including Russia, Turkey and Azerbaidjan..

Bad lack : "The existing 28 days’ detention without charge in the UK is, in comparison with other CoE member countries, one of the most extreme : In Turkey, the period is 7,5 days, in France 6 days, in Russia 5 days, and in .. the U.S. and Canada just 2 and 1 days respectively", denounced Democrat MEP Ms WOLDSETH from Norway..

woldsteth

"Numerous respected human rights organisations, including Liberty and Human Rights Watch, have expressed serious concern" "The proposed legislation ...could easily lead to extensive abuses. ...Detention for 42 days means six weeks in which one is taken away from one’s family, friends, home and livelihood only to be let off without being charged. That will destroy lives and isolate communities", she added.

- "3 years ago, the UK Government sought to increase the period of pre-charge detention from 14 days to 90 days. Not long before that, it had been only 7 days. There was a vigorous debate ...and a ...compromise was reached of 28 days. We have to ask whether there are proper safeguards in place to extend the period to 42 days. I suggest that there are fatal flaws", reminded British Conservative Clappison.

- "What sort of society holds someone in detention for 42 days and does not have to tell the person who is in prison why they are there, or explain the suspicions that arose and led to their detention? What sort of society believes that that is the way to treat its citizens? That is an appalling injustice, ...A 42-day detention period will not make the UK safer. Instead, it will be the first step to giving in to terrorists; it is saying that we are prepared to sacrifice our democratic rights and the principles for which we have stood for centuries", criticized British Liberal Michael Hanckock

hancock

"Comments made ...by Norwegian delegates are unfortunate", replied British Socialist MEP Ms.Curtis-Thomas, accusing them to "besmirch the reputation of our police force, which is one of the Best in the World", as she said, believing that "there are significant safeguards ...to ensure that individuals are not subjected to unlawful detention"

curtis

PACE "has serious doubts whether ...the draft legislation are in conformity with the ...case-law of the European Court of Human Rights. A lack of ..safeguards may lead to arbitrariness, resulting in breaches of ... liberty and ...right to a fair trial". PACE "is particularly concerned that: ..the judge ..may not be in a position to examine whether there exist reasonable grounds for suspecting that the arrested person has committed an offence;"; that "... representation by a lawyer may be inappropriately restricted or delayed;" that "information on the grounds for suspicion of a person ...may be unduly withheld.. ;" that this "may give rise to arrests without the intention to charge;", and; in general, that "prolonged detention without proper information on the grounds for arrest may constitute inhuman treatment", says Klaus De Vries' Report, adopted with 29 votes against zero.

vries

Records don't say if it took him 42 Days to draft his Report, but, at least, he knew why...

Polls

2009 EU Elections were won by Parties against Technocracy and Turkey's controversial EU bid, while the 1999-2004 Majority Abstention trend decelerated. What should be done in 2009-2014 ?

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