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Home arrow newsitems arrow Virus: Biggest Ever Trial on HCQ+AZ+Zinc Cure (3.700 Patients) Found World-Record Survival: 99,5 % !

Virus: Biggest Ever Trial on HCQ+AZ+Zinc Cure (3.700 Patients) Found World-Record Survival: 99,5 % !

Written by ACM
Monday, 25 May 2020

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*Strasbourg/Angelo Marcopolo/- In the Biggest Trial Study of HCQ+AZ+ against the Virus, just Concluded this Month, among about 3.700 Patients (i.e. the Larger Ever in the World in that area, until now), the Mortality Rate was Only ...0,5%, giving a Global Record-Breaking Survival Rate of 99,5%, as Announced Today French Professor Dr. Didier Raoult, an Experienced and Famous Infectiologist/MicroBiologist Expert, CEO of Mediterranean and Infection Hospitalo-Universitarian Institute (IHU) at Marseille City, who had been already EnTrusted by Historic French President Jacques Chirac (a Gaullist) to daft a 1st Report for the Strategy of the Country's Protection from any foreseable Risk of Epidemic, already, as Early as since the Beginning of 2000ies, (just After the SARS-1 Virus of 2003+).

- Moreover, among those circa 3.700 Patients "retrospectively", treated with HCQ+AZ+ Nowadays, "we NEVER Observed Any CARDIAC Death and Toxicity", it was added by the Two main Leaders of that New Trial, (D. Raoult and Matthieu Million), where "7.800 ECG were made" on all those Patients, by measure of Precaution.

+ Already, with  "ZERO (0) Deaths" of People Infected by the COVID-19 Virus "before 70 Years of Age", and just 8 Deaths among Only those Aged "74 to to 95 Years", in a CHQ+ Trial with More than 1.060 Patients, Concluded Previously, at the End of March, and Published at a Scientific Review on May 5, 2020, the Results appeared very Positive, (See Also Infra).

Such Landmark Results also have a Key Importance for Crucial and Topical Issues of International Health Strategy at Global Level, Nowadays :

 - Indeed, the International Health Organisation (WHO), at Nearby Geneva, had Chosen, Among about 50 Various Candidates, ("Based on Evidence from Laboratory, Animal, and [Human] Clinical Studies"), the HCQ+ as 1 Among the 3 Best "Most Promising" Candidate Drugs in the World Deserving to be Tested by its Research Program for Medical Treatment against the CoronoVirus, ("Solidarity"), with 108 Millions $ Funding and about 3.500 Patients from 17 Countries.

Competitors are Only "Remdesivir" (a Failed attempt Initially v. Ebola in Congo, where it did Not work, while Other Drugs did, But Later reportedly used in Animals v. SARS-1, Needing an IntraVenous, and Expensive, Based on Genetic Manipulations expected to Block Virus' Replication, and Backed by "Gilead" Big Pharma Corporation, holding its Patent) ; and "Lopinavir"'s Combinations, (Initialy destinated to "HIV", with "Ambiguous" Results v. SARS-1 or MERS, and "Not Encouraging" First Trials v. COVID-19, it may cause "Significant" Liver Damage, But is now Tested v. MERs in Saudi Arabia).

=> So that HCQ+ appeared, until now, to be, comparatively, the Best Hope for the World Health Organisation. A Succesful Drug already against Malaria and Arthritis, Used withOut Problem Since the 2nd World War, now a "Generic", Cheap and Simple Pill, it Might Protect Cells from Virus' Attacks, Strengthening the Natural Human Immune System, But it must Avoid Side Effects, with right Precautions. About 20 Chinese Studies reportedly were Succesful against this Virus, But a Lack of Full Published "Data" was reported, with the Exception of French Professor Raoult's Tests, that Some considered Initially "InSuficient", until his Recent Work, (which, therefore, has a Crucial Importance Nowadays).

>>> Even More Important, World-wide :  It's a Fact that the WHO has, Until Now, practicaly Excluded Vaccines from its above-mentioned International Research projects, Focused Only on Treatments and Cure, (Comp. Supra), mainly Because of a "Need for Speed", in order to "Reduce the Time" usually taken by Vaccines' testing, (may be 1 or 1,5 Year+), given the Urgency in this Deadly Virus' Crisis. In Consequence, (and given also the Facts cited Supra), at least Until Now, Serious HCQ+ Trials appeared to be, in Practice, probably the Only attainable Hope to Find a way to Urgently Save currently Threatened Human Lives throughout the Planet !

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In this Context, Previously, Trials with HCQ+AZ+ by Prof. Raoult, concluded at the End of March, had Resulted Already High enough, with a 99,1 % Survival rate. But the New Overall Results, which just Concluded on this May, (Including Almost Four Times More Patients : See Infra),  Reached an Even Higher Survival rate : 99,5 % (i.e., by Far, the Best in the World) !

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Professor Raoult's team had Initialy Tested 36 Patients, Afterwards 80, and Later 1.061, whlle Recent Rumours evoked anew a Doubling of the Number of Patients for a New, Bigger Trial,  (i.e. about 2.000). But, Finaly, he Revealed Today that it had just reached, Nowadays, almost a ...Quadripling in Tests, with about 3.700 People Affected by that Deadly Virus !

=> By so doing, obviously, this French Team largely Slamed the Accusations made Recently by a Bogus "Study", led by Dr. Mandeep Mehra, an Indo-Pakistani Cardiologist (sic !) at "Brigham and Women's Hospital" (USA), curiously Published by "LANCET" UK Review, with a Controversial Text, (Only Based on Remote, Automatic retrieval of Registry Data, by Computers' Networks, from 671 Hospitals in 6 Continents of the World, stained by at least 11 Gros Flaws ! See: http://www.eurofora.net/newsflashes/news/bogusmoveagainsthcqdrugvvirus.html), Claiming that the pro-HCQ/AZ Scientists (as Raoult etc) would have been based Only on some ..."Anecdotal Experiences" and "Small Scale Studies" (sic !) for their Theories...

But, Already, Their "6.221" copied Case-Files reportedly Registered as Including HCQ+AZ+ Treatments, in fact, are Not Equivalent to that, but Only in 1/2 or 1/3 of cases, since they doN't concern Only Azythrimycine but Also Any Other among such "    " Category of substances, of which there are 2 or 3, etc... So that, in Fact, Only some 3.110 or even just 2.070, (Perhaps Less) Might concern Professor Raoult's HCQ+AZ Protocol !             

=> I.e., a Smaller amount of strictly "Virtual" Data Remotely and Automatically Retrieved by Computer Networks, than the "More than 3.700 Patients", in Real Physical Cases, Directly Observed and Treated by Prof. Raoult's team Nowadays...                   

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- Indeed, "we made a Very, very Big Study, with More than 3.600 Patients, which Allows us to have a sufficiently Clear View of what is going on", Professor Raoult Announced Today.

- "Most of them were Treated by Associating CHQ + AZ, and, among them, Mortality is O,5%, that is to say, the Lowest in the World !", he stressed.             

=> - "So, ...Here, HCQ+ Saves Many Lives !", he Concluded.

+ Advancing (for the 1st Time), even towards a Control Group approach, he Pointed out that, "By Comparing also with Other Groups" of Patients, "who Came Too Late, Walked Out, or had Counter-Indications, because of their Coditions and Age, etc., so that they were UnAble to receive that HCQ+AZ Treatment, which gives Better Results, but Only got Other, Ordinary Treatments, there was a very Significant Difference"..., and "that's Interesting".

The "HCQ-AZ" Group included more than 3.000 Patients, while more almost 700 were "treated with Other Methods", he added later-on.

=> "Early Diagnosis, ...and Early Treatment, with at least 3 Days of HCQ-AZ, Result in a Significantly Better clinical Outcome", "with a Decreased risk of Transfer to the (Intensive Care) ICU, or  Death , ..., Decreased risk of Hospitalization ≥10 days", ... and Shorter Duration of Viral shedding", (ibid).

++ And, Now, "we Know that some things which (in the Past) had been UnderEstimated, as, f.ex., the ZINC", in fact, "Play a Role in the Severity" of cases, "f.ex. People who have a Severe Pathology, have Lower Zinc Rates than Others, in addition, also, to Other Things, too, which were, meanwhile, registered".

+++ However, "we made also", in Total, "More than 10.000 Electro-Cardio-Grams (ECG), and All were Examined by a Cardiologist", so that there wasN't any Heart Incident here at all, he pointed out. - "By the way", with the due care, "HCQ may affect People Less than... even Dolipran" (a Banal Pain-Killer) "which, in fact, is the 1st Cause in the World for Poisoning !", if taken in an inappropriate way, he extrapolated. - All and all, "we had a Total of 36 Deaths" (throughout All Trials, New and Old), "from which Not even One (1) wasn't Ever related with the Heart".

>>> In General, as a matter of Principle, Prof. Raoult's Team stands for an "Early" and "Carefully Controlled Treatment, with Safe and Well-Tolerated Drugs", "in individuals with Mild Symptoms, Before signs of Severity appear", and "paying Strict Attention ...to Contra-Indications and ...Inter-Actions with concomitant Medication", as he advised, Already in the Conclusions of the Previous Trial (of 1.061 Patients), Published at the Beginning of May, (Comp. Supra).

++++ In Parallel, Additionaly, "we have made about 130.000 Diagnostic Tests by PCR in some 50.000 Patients, including Diagnosis in about 5.000 Cases which were Treated Here", Raoult Noted Today.  

=> - "So that we were among the First to say that", in principle, "Children are Not Infected, are Not Affected" by that Virus, and - "Now, we Know Why !" Something that "we will Reveal Next Week", he promised, by the way.    

  - And "we Know that there are People who are Very Sick, and  have Big Lesions (visible only) at the Scanner, While they are Not Short of Breath", but with "Minimal" "Dyspnoea" (i.e. almost "ASymptomatic", etc).  -

 - So that, "the Evolution of (such) New Diseases canNot always be Foreseen based on that of Older Diseases : Each one may have Its Own Way to Evolve".

 =>  - Thus, "we Accumulated a Considerable Amount of Data, probaly Unique in the World", "from which we Have to Make several Conclusions, Later-on, at the Right Moment - which is Not always Similar to that of the Press-Medias : Everybody lives at his Own Pace"..., he Smiled, giving RDV in a foreseable Future.

 

(../..)

 

("Drafty-News")

 

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Former "Green-Red" German government's Foreign Minister Joschka Fischer's job at the controversial Turkish pipeline "Nabucco" was denounced as "not proper", "very bad", and "incompatible with Democracy", by the new President of EU Parliament's EuroLeft Group, German Lothar Bisky, replying to an "EuroFora" question.

For once, criticism of Joschka Fischer's doings with Turkey affecting Europe, didn't come only from the Center-Right of the political spectrum, but even from his Left side : The experienced Bisky, who has been chairing all over 1993-2009 the PDS - Die Linke party :  

- "Former Foreign Minister Joschka Fischer got involved in dealings with oil-gaz business in a foreign country, Turkey, and its controversial Nabucco pipeline. This raises questions about Democracy, also because of the well known problems of Human Rights violations in that country. Do you thing that this might be abused in order to cover up and close EU's eyes on Human Rights violations ?", "EuroFora" asked Bisky.

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- "Nabucco pipeline is (only) at the planning stage". And "there are some difficulties",  he observed from the start. But "'I don't want to get into the details of Nabucco pipeline, because I don't think that there is any point for it at the moment".
 
At any case,  "we  (EU Parliament's EuroLeft Group) strongly believe that Politicians should not get involved in the Energy Business, and all these commercial transactions", President Bisky declared on the Joschka Fiischer's affair.

- "We feel that it's something that shouldn't be done. It's not proper !"           

- "We don't think that it's compatible with Democracy either, and it gets politics into a very Bad track", Bisky went on to denounce.
                                                                                                                                                                        
- "EuroLeft  and "Die Linke" always spoke against that, saying that politicians should not get directly into the arms of private enterprises"

- "It is pretty bad if a former Minister takes a job f.ex. in a major Energy producer. So, it's an issue if a Minister who may have seen excellent opportunities, subsequently gets personally grasp of them, in very serious parts of the economy, once he has given up his (Government) job."

- "It doesn't really make politics in general look any better'", Bisky concluded.

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Earlier, this week in Strasbourg, other Journalists had also raised critical questions on former Foreign Minister Joschka Fischer's involvement in the conroversial Turkish Nabucco pipeline to the President of his own EuroParty : Kohn-Bendit of the "Greens", who, contrary to Bisky, tried to find excuses for Fischer, while criticizing his long-time partner, Schroeder for having done a similar move :

- "Shroeder was chancellor", and he "negociated" with "Russians", who gave him a job only "3 Months" after he resigned from the Government. While "Joschka Fischer", on the contrary, got a job with the controversial Turkish Nabucco pipeline only "4 Years after" he left the Government. "He didn't negociate Nabucco", so I have "no objection", Kohn Bendit claimed.

But, many Facts indicate the contrary :

Joschka Fischer was Foreign Minister in Germany from 1999 up to 2005 : I.e. from the year that EU took the controversial decision to give Turkey a "Candidate" status, until he year it started controversial "accession negotiations, (later declared "open-ended" after Sarkozy-Merkel's arrival from 2005-2007).

During that period was prepared the controversial so-called "Annan" Plan (in fact, drafted by others and attributed afterwards to the former UN SG) on Cyprus, which failed after a Popular Referendum said "No" on 2004 with a large Majoriy of 3/4 : 75%. Mainly because it was criticized for making too much concessions to the Turkish side :  Particularly by restricting Greek Cypriot Refugees' Human Right to return to their ancestral Land and/or get restitution of their Familiy Homes and private properties, usurpated by Ankara's Army since the 1974 militay invasion and continuing occupation of the northern part of Cyprus. And by weakening the Central Government, leaving to 2 "constituent States" so much powers and separate interests that more conflicts appeared inevitable, provoking the danger of a break-down in the foreseable future, with more crisis, troubles, perhaps bloodshed, etc., instead of creating an harmoniously integrated, really one federal State.

The controversial Plan was finalized on March-April 2004 at Burgenstock (Switzerland), curiously in the presence of an Envoy by the Ministry of Foreign Affairs of Germany, then governed by Joschka Fischer, but in the absence of a French and not even an European Union's Envoy, contrary to what was usually practiced on similar occasions in Switzerland (fex. in 1997 at Montreux, in 2000 at Geneva, etc).

Turkey notoriously exploited the failure of the "Annan" Plan in order to convince the EU to decide to start accession Negotiations on December 2004. This provoked an unprecedented series of Institutional Crisis inside the EU, shortly afterwards, when French and Dutch People rejected, 2 popular EuroReferenda by a majority "'No" vote to the EU Constitutional Treaty on 2005, aggraveted in 2004 a Majority Abstention to EU Elections, etc., followed by the recent Irish "No", etc.

"Nabucco" Gas pipeline was notoriously planned since ..2002. It follows an even earlier idea, for an Oil pipeline Baku-Ceyhun, which started to be prepared on 1999-2001 and was meanwhile recently completed.  

So, facts indicate that what is now at stake is based on decisions made during Joschka Fischer's term as former Foreign Minister, closely interested in Turkey's controversial EU-bid.

To the point that he now practically ...switched jobs with a poliician from Turkey, (the State which pays today openly Joschka Fischer), Mr. Ozdemir, who came earlier in Germany, got fast the nationality, and became EiuroMP in a few years, continuing now as head of the "Greens" in Germany, i.e. in Joschka's former job !...

Such astonishing facts risk, unfotunately, to give to German politician Lothar Bisky's criticism of  representative Democracy a topical meaning :

 - "We (EuroLeft Group) think that what is really at stake is Democracy. It's not only about Gas Pipelines or Energy sources", President Lothar Bisky went on to add in his reply to "EuroFora"'s question on Joscka Fischer's personal interests in the controversial Turkish "Nabuco" pipeline.

Such facts, "make People get more distance from Politics. ...People had had enough, and they are fed up !".

- "That's why we (EuroParliament's "EuroLeft" Group) want to strengthen Direct Democracy in Europe. Citizens should be involved in the (EU) Decision-making. In the end of the day, it's not going to help anyone if Politicians are always taking decisions, without involving Citizens. We want to give a voice to the People of Europe. They've got to have their say in the decisions that are taken. That's one of our absolutely fixed and steadfast views. We want more Direct Democracy in Europe. That's how it can become more effective and stronger", he concluded.

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